![]() The natural products may also promote skin wound healing by inhibiting the production of matrix metalloproteinase-9. ![]() According to the previous evidences, natural products have the potential properties for attenuating skin disorders and improving dermatologic symptoms by inhibiting inflammation through MAPK or PI3K/AKT-dependent NF-κB pathways. Endocrinologic disorders often induce cutaneous abnormalities. It provides protection and acts as a barrier against external damage factors like infectious organisms, chemicals, and allergens. Hypersecretion or hyposecretion by the adrenal gland will cause a complex cascade of hormone effects and lead to diseases, including Addison's disease, Cushing's syndrome, and congenital adrenal cortical hyperplasia. ![]() ![]() These hormones play an important role in regulating blood pressure, metabolism, and homeostasis of glucose or electrolytes. The medulla of adrenal gland secrets catecholamines. The cortex of adrenal gland produces glucocorticoid, mineralocorticoid, and androgen. ![]()
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